Objective Uniaxial Identification of Transition Points in Non-Linear Materials: Sample Application to Porcine Coronary Arteries and the Dependency of Their Pre- and Post-Transitional Moduli with Position
Freij, Jenny M.
Espino, Daniel M.
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This study aimed to develop an objective method for the elastic characterisation of pre- and post-transitional moduli of left anterior descending (LAD) porcine coronary arteries. Methods Eight coronary arteries were divided into proximal, middle and distal test specimens. Specimens underwent uniaxial extension up to 3 mm. Force–displacement measurements were used to determine the induced true stress and stretch for each specimen. A local maximum of the stretch-true stress data was used to identify a transition point. Pre- and post-transitional moduli were calculated up to and from this point, respectively. Results The mean pre-transitional moduli for all specimens was 0.76 MPa, as compared to 4.86 MPa for the post-transitional moduli. However, proximal post-transitional moduli were significantly greater than that of middle and distal test specimens (p < 0.05). Conclusion Post-transitional uniaxial properties of the LAD are dependent on location along the artery. Further, it is feasible to objectively identify a transition point between pre- and post-transitional moduli.
Cardiovascular Engineering and Technology;
Freij, J.M., Burton, H.E. and Espino, D.M. (2018) 'Objective Uniaxial Identification of Transition Points in Non-Linear Materials: Sample Application to Porcine Coronary Arteries and the Dependency of Their Pre-and Post-Transitional Moduli with Position', Cardiovascular Engineering and Technology, pp.1-8.
Article published in Cardiovascular Engineering and Technology available at https://doi.org/10.1007/s13239-018-00395-x
Cardiff Metropolitan University (Grant ID: Cardiff Metropolian (Internal))
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