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dc.contributor.authorDrane, Aimee L.
dc.contributor.authorAtencia, Rebeca
dc.contributor.authorCooper, Stephen-Mark
dc.contributor.authorRodriguez, Pablo
dc.contributor.authorSanchez, Carlos
dc.contributor.authorSimcox, Sarah
dc.contributor.authorFeltrer, Yedra
dc.contributor.authorPeck, Bruce
dc.contributor.authorEng, Jaclyn
dc.contributor.authorMoittie, Sophie
dc.contributor.authorUnwin, Steve
dc.contributor.authorHowatson, Glyn
dc.contributor.authorOxborough, David
dc.contributor.authorStembridge, Mike
dc.contributor.authorShave, Rob
dc.date.accessioned2019-02-05T10:04:21Z
dc.date.available2019-02-05T10:04:21Z
dc.date.issued2019-06
dc.identifier.citationDrane, A.L., Atencia, R., Cooper, S-M., Rodriguez, P., Sanchez, C., Simcox, S., Feltrer, Y., Peck, B., Eng, J., Moittie, S., Unwin, S., Howatson, G., Oxborough, D., Stembridge, M.R. and Shave, R.E. (In Press) ‘Cardiac structure and function characterized across age groups and between sexes in healthy wild-born captive chimpanzees (Pan troglodytes) living in sanctuaries’, American Journal of Veterinary Research. 80, (6), pp. 547-557. https://doi.org/10.2460/ajvr.80.6.547en_US
dc.identifier.issn1943-5681
dc.identifier.urihttp://hdl.handle.net/10369/10263
dc.descriptionArticle published in American Journal of Veterinary Research available at https://doi.org/10.2460/ajvr.80.6.547en_US
dc.descriptionClosed deposit
dc.description.abstractObjective: To comprehensively characterize cardiac structure and function, from infancy to adulthood, in male and female wild-born captive chimpanzees (Pan troglodytes) living in sanctuaries. Animals: 290 wild-born captive chimpanzees. Procedures: Physical and echocardiographic examinations were performed on anesthetized chimpanzees in 3 sanctuaries in Africa between October 2013 and May 2017. Results were evaluated across age groups and between sexes, and potential differences were assessed with multiple 1-way independent Kruskal-Wallis tests. Results: Results indicated that left ventricular diastolic and systolic function declined at a younger age in males than in females. Although differences in right ventricular diastolic function were not identified among age groups, right ventricular systolic function was lower in adult chimpanzees (> 12 years old), compared with subadult (8 to 12 years old) and juvenile (5 to 7 years old) chimpanzees. In addition, male subadult and adult chimpanzees had larger cardiac wall dimensions and chamber volumes than did their female counterparts. Conclusions and Clinical Relevance: Results of the present study provided useful reference intervals for cardiac structure and function in captive chimpanzees categorized on the basis of age and sex; however, further research is warranted to examine isolated and combined impacts of blood pressure, age, body weight, and anaesthetic agents on cardiac structure and function in chimpanzees.en_US
dc.description.sponsorshipInternational Primate Heart Projecten_US
dc.language.isoenen_US
dc.publisherAmerican Veterinary Medical Associationen_US
dc.relation.ispartofseriesAmerican Journal of Veterinary Research;
dc.titleCardiac structure and function characterized across age groups and between sexes in healthy wild-born captive chimpanzees (Pan troglodytes) living in sanctuariesen_US
dc.typeArticleen_US
dc.identifier.doihttps://doi.org/10.2460/ajvr.80.6.547
dcterms.dateAccepted2018-11-23
rioxxterms.funderCardiff Metropolitan Universityen_US
rioxxterms.identifier.projectCardiff Metropolian (Internal)en_US
rioxxterms.versionNAen_US
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/under-embargo-all-rights-reserveden_US
rioxxterms.licenseref.startdate2019-02-05
dc.refexceptionThe publication concerned actively disallows open-access deposit in a repository, and was the most appropriate publication for the output
rioxxterms.freetoread.startdate2100-01-01
rioxxterms.funder.project37baf166-7129-4cd4-b6a1-507454d1372een_US


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