Impact of prenatal exercise on maternal harms, labour and delivery outcomes: a systematic review and meta-analysis
Jaramillo Garcia, Alejandra
Meah, Victoria L.
BMJ Publishing Group
MetadataShow full item record
Objective. We aimed to identify the relationship between maternal prenatal exercise and birth complications, and neonatal and childhood morphometric, metabolic and developmental outcomes. Design. Systematic review with random-effects meta-analysis and meta-regression. Data sources. Online databases were searched up to 6 January 2017. Study eligibility criteria. Studies of all designs were eligible (except case studies and reviews) if published in English, Spanish or French, and contained information on the relevant population (pregnant women without contraindication to exercise), intervention (subjective/objective measures of frequency, intensity, duration, volume or type of exercise, alone (‘exercise-only’) or in combination with other intervention components (eg, dietary; ‘exercise+cointervention’)), comparator (no exercise or different frequency, intensity, duration, volume, type or trimester of exercise) and outcomes (preterm birth, gestational age at delivery, birth weight, low birth weight (<2500 g), high birth weight (>4000 g), small for gestational age, large for gestational age, intrauterine growth restriction, neonatal hypoglycaemia, metabolic acidosis (cord blood pH, base excess), hyperbilirubinaemia, Apgar scores, neonatal intensive care unit admittance, shoulder dystocia, brachial plexus injury, neonatal body composition (per cent body fat, body weight, body mass index (BMI), ponderal index), childhood obesity (per cent body fat, body weight, BMI) and developmental milestones (including cognitive, psychosocial, motor skills)). Results. A total of 135 studies (n=166 094) were included. There was ‘high’ quality evidence from exercise-only randomised controlled trials (RCTs) showing a 39% reduction in the odds of having a baby >4000 g (macrosomia: 15 RCTs, n=3670; OR 0.61, 95% CI 0.41 to 0.92) in women who exercised compared with women who did not exercise, without affecting the odds of growth-restricted, preterm or low birth weight babies. Prenatal exercise was not associated with the other neonatal or infant outcomes that were examined. Conclusions. Prenatal exercise is safe and beneficial for the fetus. Maternal exercise was associated with reduced odds of macrosomia (abnormally large babies) and was not associated with neonatal complications or adverse childhood outcomes.
British Journal of Sports Medicine;
Davenport, M.H., Ruchat, S.M., Sobierajski, F., Poitras, V.J., Gray, C.E., Yoo, C., Skow, R.J., Garcia, A.J., Barrowman, N., Meah, V.L., Nagpal, T.S. et al (2019) 'Impact of prenatal exercise on maternal harms, labour and delivery outcomes: a systematic review and meta-analysis', British Journal of Sports Medicine, 53(2), pp.99-107
Article published in British Journal of Sports Medicine on 18 October 2018, available at: http://dx.doi.org/10.1136/bjsports-2018-099836.
Cardiff Metropolitan University (Grant ID: Cardiff Metropolian (Internal))
- Import 
Showing items related by title, author, subject and abstract.
Beeton, Michael L.; Maxwell, Nicola C.; Chalker, Victoria J.; Aboklaish, Ali; Spiller, Owen (American Academy of Pediatrics, 2016-07-14)Isolation of Ureaplasma spp. from preterm neonates and the association with development of bronchopulmonary dysplasia has been previously investigated. However, few studies have contrasted the nature of infection in twins. ...
The Paradoxical Effects of Chronic Intra-Amniotic Ureaplasma parvum Exposure on Ovine Fetal Brain Development Gussenhoven, R.; Ophelders, D.R.M.G.; Kemp, M.W.; Payne, M.S.; Spiller, O.B.; Beeton, Michael L.; Stocks, S.J.; Cillero-Pastor, B.; Barre, F.P.Y.; Heeren, R.M.A.; Kessels, L.; Stevens, B.; Rutten, B.P.; Kallapur, S.G.; Jobe, A.H.; Kramer, B.W.; Wolfs, T.G.A.M. (Karger, 2017-08-29)Chorioamnionitis is associated with adverse neurodevelopmental outcomes in preterm infants. Ureaplasma spp. are the microorganisms most frequently isolated from the amniotic fluid of women diagnosed with chorioamnionitis. ...
The primary prevention of cardiovascular disease in women with an emphasis on physical activity: A social marketing approach Sawyer, Ceinwen (Cardiff Metropolitan University, 2012)The policies of the Welsh Assembly Government (WAG) regarding the health of the Welsh population are underpinned by a social marketing approach. This is where the individual is supported in their efforts to take personal ...