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dc.contributor.authorCooper, Rose
dc.contributor.authorKirketerp-Møller, Klaus
dc.identifier.citationCooper, R. and Kirketerp-Møller, K. (2018) 'Non-antibiotic antimicrobial interventions and antimicrobial stewardship in wound care', Journal of Wound Care, 27(6), pp.355-377. DOI: 10.12968/jowc.2018.27.6.355.en_US
dc.descriptionArticle published in Journal of Wound Care on 08 June 2018, available at:
dc.description.abstractControl of wound infection today relies largely on antibiotics, but the continual emergence of antibiotic-resistant microorganisms threatens a return to the pre-antibiotic era when physicians used antiseptics to prevent and manage infection. Some of those antiseptics are still used today, and others have become available. A diverse variety of non-antibiotic antimicrobial interventions are found on modern formularies. Unlike the mode of action of antibiotics, which affect specific cellular target sites of pathogens, many non-antibiotic antimicrobials affect multiple cellular target sites in a non-specific way. Although this reduces the likelihood of selecting for resistant strains of microorganisms, some have emerged and cross-resistance between antibiotics and antiseptics has been detected. With the prospect of a post-antibiotic era looming, ways to maintain and extend our antimicrobial armamentarium must be found. In this narrative review, current and emerging non-antibiotic antimicrobial strategies will be considered and the need for antimicrobial stewardship in wound care will be explained.en_US
dc.publisherMark Allen Healthcareen_US
dc.relation.ispartofseriesJournal of Wound Care;
dc.titleNon-antibiotic antimicrobial interventions and antimicrobial stewardship in wound careen_US
rioxxterms.funderCardiff Metropolitan Universityen_US
rioxxterms.identifier.projectCardiff Metropolian (Internal)en_US

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