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dc.contributor.authorKelly, Claire
dc.contributor.authorCaldwell, Maeve
dc.identifier.citationKelly, C.M. and Caldwell, M.A. (2018) 'Derivation of Neural Stem Cells from the Developing and Adult Human Brain'. In: Buzanska, L. Human Neural Stem Cells. Springer: Cham, pp.3-20.en_US
dc.descriptionChapter 1 in Human Neural Stem Cells (2018), available at:
dc.description.abstractNeural stem cells isolated from the developing and adult brain are an ideal source of cells for use in clinical applications such as cell replacement therapy. The clear advantage of these cells over the more commonly utilised embryonic and pluripotent stem cells is that they are already neurally committed. Of particular importance is the fact that these cells don’t require the same level of in vitro culture that can be cost and labour intensive. Foetal neural stem cells can be readily derived from the foetal brain and expand in culture over time. Similarly, adult stem cells have been explored for their potential in vitro and in vivo animal models. In this chapter we identify the progress made in developing these cells as well as the advantages of taking them forward for clinical use.en_US
dc.relation.ispartofseriesHuman Neural Stem Cells;
dc.titleDerivation of Neural Stem Cells from the Developing and Adult Human Brainen_US
dc.typeBook chapteren_US

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