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dc.contributor.authorEnnis, Stuart
dc.contributor.authorLobley, Grace
dc.contributor.authorWorrall, Sandra
dc.contributor.authorPowell, Richard
dc.contributor.authorKimani, Peter
dc.contributor.authorKhan, Amir Jahan
dc.contributor.authorBanerjee, Prithwish
dc.contributor.authorBarker, Thomas
dc.contributor.authorMcGregor, Gordon
dc.date.accessioned2019-05-14T07:54:38Z
dc.date.available2019-05-14T07:54:38Z
dc.date.issued2018-03-23
dc.identifier.citationEnnis, S., Lobley, G., Worrall, S., Powell, R., Kimani, P.K., Khan, A.J., Banerjee, P., Barker, T. and McGregor, G. (2018) 'Early initiation of post-sternotomy cardiac rehabilitation exercise training (SCAR): study protocol for a randomised controlled trial and economic evaluation', BMJ Open, 8(3), p.e019748. DOI: 10.1136/bmjopen-2017-019748.en_US
dc.identifier.issn2044-6055
dc.identifier.urihttp://hdl.handle.net/10369/10488
dc.descriptionArticle published in BMJ Open on 23 March 2018, available open access at: http://dx.doi.org/10.1136/bmjopen-2017-019748.en_US
dc.description.abstractIntroduction: Current guidelines recommend abstinence from supervised cardiac rehabilitation (CR) exercise training for 6 weeks post-sternotomy. This practice is not based on empirical evidence, thus imposing potentially unnecessary activity restrictions. Delayed participation in CR exercise training promotes muscle atrophy, reduces cardiovascular fitness and prolongs recovery. Limited data suggest no detrimental effect of beginning CR exercise training as early as 2 weeks post-surgery, but randomised controlled trials are yet to confirm this. The purpose of this trial is to compare CR exercise training commenced early (2 weeks post-surgery) with current usual care (6 weeks post-surgery) with a view to informing future CR guidelines for patients recovering from sternotomy. Methods and analysis: In this assessor-blind randomised controlled trial, 140 cardiac surgery patients, recovering from sternotomy, will be assigned to 8 weeks of twice-weekly supervised CR exercise training commencing at either 2 weeks (early CR) or 6 weeks (usual care CR) post-surgery. Usual care exercise training will adhere to current UK recommendations. Participants in the early CR group will undertake a highly individualised 2–3 week programme of functional mobility, strength and cardiovascular exercise before progressing to a usual care CR programme. Outcomes will be assessed at baseline (inpatient), pre-CR (2 or 6 weeks post-surgery), post-CR (10 or 14 weeks post-surgery) and 12 months. The primary outcome will be change in 6 min walk distance. Secondary outcomes will include measures of functional fitness, quality of life and cost-effectiveness. Ethics and dissemination: Recruitment commenced on July 2017 and will complete by December 2019. Results will be disseminated via national governing bodies, scientific meetings and peer-reviewed journals. Trial registration number: NCT03223558; Pre-results.en_US
dc.description.sponsorshipThis work was supported by the Jeremy Pilcher Memorial Fund (UHCW), the Medical & Life Sciences Research Fund and Atrium Health Ltd, Coventryen_US
dc.language.isoenen_US
dc.publisherBMJ Publishing Groupen_US
dc.relation.ispartofseriesBMJ Open;
dc.titleEarly initiation of post-sternotomy cardiac rehabilitation exercise training (SCAR): study protocol for a randomised controlled trial and economic evaluationen_US
dc.typeArticleen_US
dc.identifier.doihttp://dx.doi.org/10.1136/bmjopen-2017-019748
dcterms.dateAccepted2018-02-23
rioxxterms.funderCardiff Metropolitan Universityen_US
rioxxterms.identifier.projectCardiff Metropolian (Internal)en_US
rioxxterms.versionVoRen_US
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/en_US
rioxxterms.licenseref.startdate2019-05-14
rioxxterms.funder.project37baf166-7129-4cd4-b6a1-507454d1372een_US


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