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dc.contributor.authorBeeton, Michael L.
dc.contributor.authorPayne, Matthew S.
dc.contributor.authorJones, L.
dc.date.accessioned2019-05-21T09:34:56Z
dc.date.available2019-05-21T09:34:56Z
dc.date.issued2019-07-03
dc.identifier.citationBeeton, M.L., Payne, M.S. and Jones, L. (2019) 'The Role of Ureaplasma spp. in the Development of Nongonococcal Urethritis and Infertility among Men', Clinical Microbiology Reviews, 32(4), pp.e00137-18.
dc.identifier.issn1098-6618
dc.identifier.urihttp://hdl.handle.net/10369/10515
dc.descriptionArticle published in Clinical Microbiology Reviews on 03 July 2019, available at: https://doi.org/10.1128/CMR.00137-18.en_US
dc.description.abstractUreaplasma spp. are a genus of bacteria for which two human associated species exist; Ureaplasma urealyticum and Ureaplasma parvum. Their definition as a pathogen in the context of non-gonococcal urethritis and infertility among males remains highly controversial, largely due to historically high isolation rates of these bacteria from the urethra of seemingly healthy men. This review summarises the emerging evidence suggesting a true pathogenic role of these bacteria under specific conditions, which we term as risk factors. We examine the historical, clinical and experimental studies which support a causal role for Ureaplasma spp in the development of NGU as well as some of the proposed mechanisms behind the association of Ureaplasma spp. and the development of infertility. Finally, we discuss the potential for developing a case-by-case risk-based approach towards the management of men who present with seemingly idiopathic NGU, but are positive for Ureaplasma spp.en_US
dc.language.isoenen_US
dc.publisherAmerican Society for Microbiologyen_US
dc.relation.ispartofseriesClinical Microbiology Reviews;
dc.titleThe role of Ureaplasma spp. in the development of non-gonococcal urethritis and infertility among menen_US
dc.typeArticleen_US
dc.identifier.doihttps://doi.org/10.1128/CMR.00137-18
dcterms.dateAccepted2019-05-15
rioxxterms.funderCardiff Metropolitan Universityen_US
rioxxterms.identifier.projectCardiff Metropolian (Internal)en_US
rioxxterms.versionAMen_US
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by-nc/4.0/en_US
rioxxterms.licenseref.startdate2019-05-21
rioxxterms.freetoread.startdate2020-01-03
rioxxterms.funder.project37baf166-7129-4cd4-b6a1-507454d1372een_US


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