• English
    • Welsh
  • Welsh 
    • English
    • Welsh
  • Mewngofnodi
Chwilio'r safle:
  • Hafan
  • Ymchwil ym Met Caerdydd
  • Gwasanaethau Llyfrgell
  • Cysylltu â Ni
Gweld eitem 
  • Hafan DSpace
  • Cardiff School of Art and Design
  • National Centre for Product Design and Development Research (PDR)
  • Technology-led design
  • Gweld eitem
  • Hafan DSpace
  • Cardiff School of Art and Design
  • National Centre for Product Design and Development Research (PDR)
  • Technology-led design
  • Gweld eitem
JavaScript is disabled for your browser. Some features of this site may not work without it.

The Effect of Mechanical Overloading on Surface Roughness of the Coronary Arteries

Thumbnail
Gweld/agor
Publisher's PDF (5.537Mb)
Awdur
Burton, Hanna
Espino, Daniel
Dyddiad
2019-01-23
Dyddiad derbyn
2019-01-01
Math
Article
Cyhoeddwr
Hindawi
ISSN
1754-2103
Metadata
Dangos cofnod eitem llawn
Crynodeb
Background. Surface roughness can be used to identify disease within biological tissues. Quantifying surface roughness in the coronary arteries aids in developing treatments for coronary heart disease. This study investigates the effect of extreme physiological loading on surface roughness, for example, due to a rupture of an artery. Methods. The porcine left anterior descending (LAD) coronary arteries were dissected ex vivo. Mechanical overloading was applied to the arteries in the longitudinal direction to simulate extreme physiological loading. Surface roughness was calculated from three-dimensional reconstructed images. Surface roughness was measured before and after damage and after chemical processing to dehydrate tissue specimens. Results. Control specimens confirmed that dehydration alone results in an increase of surface roughness in the circumferential direction only. No variation was noted between the hydrated healthy and damaged specimens, in both the longitudinal ( and ) and circumferential ( and ) directions. After dehydration, an increase in surface roughness was noted for damaged specimens in both the longitudinal () and circumferential () directions. Conclusions. Mechanical overloading applied in the longitudinal direction did not significantly affect surface roughness. However, when combined with chemical processing, a significant increase in surface roughness was noted in both the circumferential and longitudinal directions. Mechanical overloading causes damage to the internal constituents of the arteries, which is significantly noticeable after dehydration of tissue.
Cyfnodolyn/trafodion cynhadledd
Applied Bionics and Biomechanics;
Dyfyniad
Burton, H.E. and Espino, D.M. (2019) 'The Effect of Mechanical Overloading on Surface Roughness of the Coronary Arteries', Applied Bionics and Biomechanics. DOI: 10.1155/2019/2784172.
URI
http://hdl.handle.net/10369/10687
Dynodwr Gwrthrych Digidol (DOI)
https://doi.org/10.1155/2019/2784172
Disgrifiad
Article published in Applied Bionics and Biomechanics on 23 January 2019, available open access at: https://doi.org/10.1155/2019/2784172.
Hawliau
https://creativecommons.org/licenses/by/4.0/
Nawdd
Cardiff Metropolitan University (Grant ID: Cardiff Metropolian (Internal))
HEB was funded by an Engineering and Physical Sciences Research Council scholarship (M114612B). The materials and testing equipment used in this study was funded by an Arthritis Research UK grant (H0671). This study was partly funded by an Innovation and Research Award from the Institute of Physics and Engineering in Medicine.
Casgliadau
  • Technology-led design [51]

Eitemau perthynol

Yn dangos eitemau sy’n perthyn drwy deitl, awdur, pwnc a chrynodeb.

  • Braslun bawd

    Effects of freezing, fixation and dehydration on surface roughness properties of porcine left anterior descending coronary arteries 

    Burton, Hanna; Williams, Richard; Espino, Daniel (Elsevier, 2017-06-22)
    Background To allow measurements of surface roughness to be made of coronary arteries using various imaging techniques, chemical processing, such as fixation and dehydration, is commonly used. Standard protocols suggest ...
  • Braslun bawd

    Dynamic viscoelasticity and surface properties of porcine left anterior descending coronary arteries 

    Burton, Hanna; Freij, Jenny M.; Espino, Daniel M. (Springer, 2016-12-12)
    The aim of this study was, for the first time, to measure and compare quantitatively the viscoelastic properties and surface roughness of coronary arteries. Porcine left anterior descending coronary arteries were dissected ...
  • Braslun bawd

    Multiscale three-dimensional surface reconstruction and surface roughness of porcine left anterior descending coronary arteries 

    Burton, Hanna; Cullinan, Rachael; Jiang, Kyle; Espino, Daniel M. (Royal Society, 2019-09-11)
    The aim of this study was to investigate the multiscale surface roughness characteristics of coronary arteries, to aid in the development of novel biomaterials and bioinspired medical devices. Porcine left anterior descending ...

Pori

Holl Dspace Met CaerdyddCymunedau a ChasgliadauYn ôl dyddiad cyhoeddiAwduronTeitlauPynciauY casgliad hwnYn ôl dyddiad cyhoeddiAwduronTeitlauPynciau

Fy Nghyfrif

Mewngofnodi

Statistics

Most Popular ItemsStatistics by CountryMost Popular Authors

DSpace software copyright © 2002-2015  DuraSpace
Cysylltu â ni | Anfon adborth | Gweinyddwr