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A Genetic Lung Cancer Susceptibility Test may have a Positive Effect on Smoking Cessation

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Author
Kammin, Tammy
Fenton, Andrew
Thirlaway, Kathryn
Date
2014-11-19
Acceptance date
2014-08-27
Type
Article
Publisher
Springer
ISSN
1573-3599
Metadata
Show full item record
Abstract
Smoking increases the risk of developing lung cancer. Genetic loci have been identified which could form the basis of a lung cancer susceptibility test; but little is known whether such a test would interest or motivate those trying to quit smoking. To address this, we investigated the attitudes of people trying to quit smoking towards genetic susceptibility testing for lung cancer. Participant's attitudes to topics associated with lung cancer susceptibility testing were assessed; were they interested in genetic testing? What impact would a hypothetical high‐ or low‐ risk result have on smoking cessation? 680 self‐completion questionnaires were given to individuals attending National Health Service stop smoking clinics in three different areas of the United Kingdom between 2011 and 2012. 139 questionnaires were returned, giving a 20 % response rate. Participants expressed an interest in a genetic susceptibility test for lung cancer and almost all reported that a high‐risk result would increase their motivation to stop smoking. However, many participants had a neutral attitude towards a low‐risk result. Most participants agreed their smoking habit could lead to lung cancer. Lung cancer susceptibility testing may be a useful incentive to help people quit smoking. This study suggests the need for genetic services to work with smoking cessation teams if routine testing becomes available in the future.
Journal/conference proceeding
Journal of Genetic Counseling;
Citation
Kammin, T., Fenton, A.K. and Thirlaway, K. (2015) 'A genetic lung cancer susceptibility test may have a positive effect on smoking cessation', Journal of Genetic Counseling, 24(3), pp.522-531.
URI
http://hdl.handle.net/10369/10792
DOI
https://doi.org/10.1007/s10897-014-9766-8
Description
Article published in Journal of Genetic Counseling on 19 November 2014 (online), freely available at: https://doi.org/10.1007/s10897-014-9766-8.
Rights
http://www.rioxx.net/licenses/all-rights-reserved
Sponsorship
Cardiff Metropolitan University (Grant ID: Cardiff Metropolian (Internal))
Collections
  • Health and Risk Management [171]

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