Inner ear pressure evaluation using wideband tympanometry in children with Large Vestibular Aqueduct Syndrome (LVAS): A pilot study

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Author
Zhang, Lifang
Wang, Jie
Zhao, Fei
Li, Yongxin
Date
2019-09-19Acceptance date
2019-09-18
Type
Article
Publisher
Elsevier
ISSN
0165-5876
1872-8464
Metadata
Show full item recordAbstract
Objective
To investigate middle ear function in children with Large Vestibular Aqueduct Syndrome (LVAS) to explore the feasibility of measuring inner ear pressure using Wideband tympanometry (WBT).
Methods
13 young children with LVAS were recruited. WBT and other audiological measurements i.e., Auditory Steady State Response (ASSR), Auditory Brain Stem Response (ABR), and Distorted Product Otoacoustic Emissions (DPOAE) were performed. Absorbance under ambient and peak pressure were compared with normative data, and analyzed using a one sample t-test.
Results
Average absorbance in children with LVAS was significantly lower than normative data under ambient pressure at 1000, 1189, 1296, 2000 Hz and 4000 Hz. Absorbance under peak pressure was also significantly lower at 707, 794, 917, 1000, 1189, 1297, 1498 and 2000 Hz. However, absorbance was higher than standard values above 4000 Hz under ambient and peak pressure. It was also higher under ambient pressure at frequencies below 500 Hz.
Conclusion
The special characteristics of middle ear function found in children with Large Vestibular Aqueduct Syndrome (LVAS) indicate that WBT offers a sensitive and non-invasive method to evaluate inner ear pressure indirectly.
Journal/conference proceeding
International Journal of Pediatric Otorhinolaryngology;
Citation
Zhang, L., Wang, J., Zhao, F. and Li, Y. (2020) 'Inner ear pressure evaluation using wideband tympanometry in children with Large Vestibular Aqueduct Syndrome (LVAS): A pilot study', International Journal of Pediatric Otorhinolaryngology, 128, p.109690.
Description
Article published in International Journal of Pediatric Otorhinolaryngology available at https://doi.org/10.1016/j.ijporl.2019.109690
Sponsorship
Cardiff Metropolitan University (Grant ID: Cardiff Metropolian (Internal))
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