Vaccine repurposing approach for preventing COVID 19: can MMR vaccines reduce morbidity and mortality?
Author
Anbarasu, Anand
Ramaiah, Sudha
Livingstone, Paul
Date
2020-06-05Acceptance date
2020-05-18
Type
Article
Publisher
Taylor and Francis
ISSN
2164-554X
Metadata
Show full item recordAbstract
The coronavirus disease (COVID-19) is resulting in millions of infected individuals with several hundred thousands dead throughout the world. Amidst all the havoc, one interesting observation in the present COVID-19 pandemic is the negligible symptoms in the young; particularly children below 10 years of age. We assume the extensive pediatric vaccination with MMR vaccines followed globally could have resulted in innate immune responses, e.g., induction of interferons (IFNs) and activated natural killer (NK) cells, thereby offering natural immunity against SARS-CoV-2 in the young population. Possible cross-protective innate immunity offered by MMR vaccination prompted us to suggest repurposing MMR vaccination for immuno-prophylaxis against COVID-19.
Journal/conference proceeding
Human Vaccines and Immunotherapeutics;
Citation
Anbarasu, A., Ramaiah, S. and Livingstone, P. (2020) 'Vaccine repurposing approach for preventing COVID 19: can MMR vaccines reduce morbidity and mortality?', Human Vaccines & Immunotherapeutics, pp.1-2.
Description
Article published in Human Vaccines and Immunotherapeutics on 05 June 2020, freely available at: https://doi.org/10.1080/21645515.2020.1773141.
Sponsorship
Cardiff Metropolitan University (Grant ID: Cardiff Metropolian (Internal))
Indian council of Medical Research (Government of India, agency) research grant IRIS ID: 2019-0810.
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