Vaccine repurposing approach for preventing COVID 19: can MMR vaccines reduce morbidity and mortality?
Taylor and Francis
MetadataShow full item record
The coronavirus disease (COVID-19) is resulting in millions of infected individuals with several hundred thousands dead throughout the world. Amidst all the havoc, one interesting observation in the present COVID-19 pandemic is the negligible symptoms in the young; particularly children below 10 years of age. We assume the extensive pediatric vaccination with MMR vaccines followed globally could have resulted in innate immune responses, e.g., induction of interferons (IFNs) and activated natural killer (NK) cells, thereby offering natural immunity against SARS-CoV-2 in the young population. Possible cross-protective innate immunity offered by MMR vaccination prompted us to suggest repurposing MMR vaccination for immuno-prophylaxis against COVID-19.
Human Vaccines and Immunotherapeutics;
Anbarasu, A., Ramaiah, S. and Livingstone, P. (2020) 'Vaccine repurposing approach for preventing COVID 19: can MMR vaccines reduce morbidity and mortality?', Human Vaccines & Immunotherapeutics, pp.1-2.
Article published in Human Vaccines and Immunotherapeutics on 05 June 2020, freely available at: https://doi.org/10.1080/21645515.2020.1773141.
Cardiff Metropolitan University (Grant ID: Cardiff Metropolian (Internal))
Indian council of Medical Research (Government of India, agency) research grant IRIS ID: 2019-0810.
Showing items related by title, author, subject and abstract.
Thirlaway, Kathryn; Lukeman, H. (Health Protection Agency in association with the Scottish Centre for Infection and Environmental Health, 2003-06-01)A new conjugated meningococcal group C vaccine became available in November 1999. This study set out to record the vaccination status of all first year undergraduates attending a university in South Wales in 2000-01 and ...
Modulation of the innate immune response by Middle East Respiratory Syndrome Coronavirus Spike protein Al Rashdi, Mohmed Abdulla Omar (Cardiff Metropolitan University, 2017-06-01)Background: Middle East Respiratory Syndrome Coronavirus (MERS-CoV) was identified in 2012 as an emerging pathogen linked to patients presenting with serious respiratory illness complicated with renal impairment and to a ...
Gunston, Sophie (Cardiff Metropolitan University, 2017-06-01)The human papillomavirus (HPV) is a highly transmissible virus with over 200 genotypes discovered, categorised based of their risk status. Recurrent infection with the carcinogenic high risk genotypes is responsible for ...