Comparison between Modelflow® and echocardiography in the determination of cardiac output during and following pregnancy at rest and during exercise
Meah, Victoria L.
Stöhr, Eric J.
Facultad de Educación
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During pregnancy, assessment of cardiac output (Q ̇), a fundamental measure of cardiovascular function, provides important insight into maternal adaptation. However, methods for dynamic Q ̇ measurement require validation. The purpose of this study was to estimate the agreement of Q ̇ measured by echocardiography and Modelflow® at rest and during submaximal exercise in non-pregnant (n = 18), pregnant (n = 15, 22-26 weeks gestation) and postpartum women (n = 12, 12-16 weeks post-delivery). Simultaneous measurements of Q ̇ derived from echocardiography [criterion] and Modelflow® were obtained at rest and during low-moderate intensity (25% and 50% peak power output) cycling exercise and compared using Bland-Altman analysis and limits of agreement. Agreement between echocardiography and Modelflow® was poor in non-pregnant, pregnant and postpartum women at rest (mean difference ± SD: -1.1 ± 3.4; -1.2 ± 2.9; -1.9 ± 3.2 L.min-1), and this remained evident during exercise. The Modelflow® method is not recommended for Q ̇ determination in research involving young, healthy non-pregnant and pregnant women at rest or during dynamic challenge. Previously published Q ̇ data from studies utilising this method should be interpreted with caution.
Journal of Human Sport and Exercise;
Meah, V.L., Backx, K., Shave, R.E., Stöhr, E.J. and Cooper, S.M. (2020) 'Comparison between Modelflow® and echocardiography in the determination of cardiac output during and following pregnancy at rest and during exercise', Journal of Human Sport and Exercise.
Article published in Journal of Human Sport and Exercise on 23 July 2020, available open access at: https://doi.org/10.14198/jhse.2022.171.12.
Cardiff Metropolitan University (Grant ID: Cardiff Metropolian (Internal))
- Sport Research Groups 
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Meah, Victoria L.; Backx, Karianne; Cockcroft, John R.; Shave, Rob; Stöhr, Eric J. (Wiley, 2019-09-04)Objective: To evaluate left ventricular (LV) mechanics in the second trimester of healthy pregnancy and to determine the influence of underpinning hemodynamics (heart rate (HR), preload and afterload) on LV mechanics ...
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