A sympathetic view of blood pressure control at high altitude: new insights from microneurographic studies
Simpson, Lydia Louise
Steinback, Craig D.
Moore, Jonathan P.
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High altitude (HA) hypoxia is a potent activator of the sympathetic nervous system, eliciting increases in sympathetic vasomotor activity. Microneurographic evidence of HA sympathoexcitation dates back to the late 20thcentury, yet only recently have the characteristics and underpinning mechanisms been explored in detail. This review summarises recent findings and highlightstheimportance of HA sympathoexcitation for theregulation of blood pressure in lowlanders and indigenous highlanders. In addition, this review will identify gaps in our knowledge and corresponding avenues for future study.
Simpson, L.L., Steinback, C.D., Stembridge, M. and Moore, J.P. (2020) 'A sympathetic view of blood pressure control at high altitude: new insights from microneurographic studies', Experimental Physiology. https://doi.org/10.1113/EP089194
Article published in Experimental Physiology available open access at https://doi.org/10.1113/EP089194
Cardiff Metropolitan University (Grant ID: Cardiff Metropolian (Internal))
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