An investigation into the association between markers of obesity and markers of arterial stiffness
University of Wales Institute Cardiff
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Background: Increased body fat percentage is thought to be associated with arterial stiffness and increased cardiovascular risk. The aim of the study was to investigate the effect that obesity had on augmentation index. This study investigates two markers of arterial stiffness and two markers of obesity. Method: A total of 30 participant were recruited for the study, the participants had to be free from ongoing illness, not currently on any medication and not pregnant. Participants of the study also had to be non-smokers. Participants were weight and measured, body mass index (BMI) was then determined weight divided by height squared (kg/m2). Participants were also required to have their augmentation index taken using a sphygmocor CP analysis system, and their body fat percentage calculated using bioelectrical impedance. The results were then statistically analysed using both Minitab and SPSS, only relationships that had a P-value of less than 0.05 were considered statistically significant. Results: The relationships between body fat percentage, BMI, and augmentation index and pulse pressure were all statistically insignificant as they had P-values greater than 0.05. The P-values for the relationships between body fat percentage and augmentation index, and body fat percentage and pulse pressure were 0.153 and 0.185 respectively. The P-values for BMI and augmentation index, and BMI and pulse pressure were 0.674 and 0.101 respectively. Conclusion: From the results of the study no conclusions can be drawn about the relationship between body fat percentage, BMI, and augmentation index and pulse pressure. Further investigation needs to take place involving a wider sample population.
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