Alcohol and violence and the possible role of serotonin
John Wiley & Sons, Ltd
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Background There is undisputed evidence linking alcohol consumption and violence and other forms of aggressive behaviour, and also linking aggression with dysfunction of the brain indolylamine serotonin (5-hydroxytryptamine or 5-HT). Alcohol consumption also causes major disturbances in the metabolism of brain serotonin. In particular, acute alcohol intake depletes brain serotonin levels in normal (non-alcohol-dependent) subjects. On the basis of the above statements, it is suggested that, at the biological level, alcohol may induce aggressive behaviour in susceptible individuals, at least in part, by inducing a strong depletion of brain serotonin levels. Aims In this article, evidence supporting these interrelationships and interactions will be summarized and discussed, the alcohol-serotonin-aggression hypothesis will be reiterated, and potential intervention strategies will be proposed. Copyright © 2003 Whurr Publishers Ltd.
Criminal Behaviour and Mental Health
Badawy, Abdullah (2003). Criminal Behaviour and Mental Health 13 (1), pp.31-44
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