Exercise-induced cardiac troponin release: real-life clinical confusion
van Dijk, A.
Hopman, Maria T.E.
MetadataDangos cofnod eitem llawn
Exercise training represents a successful and powerful strategy to prevent future cardiovascular disease. Paradoxically, performance of exercise is also associated with an increased risk of acute cardiac events. Accordingly, patients may present to hospital with cardiac symptoms following a bout of unaccustomed physical effort (e.g. exercise). Current guidelines for the identification of an acute myocardial infarction (AMI) importantly depend on the presence of cardiac troponin as a highly sensitive marker of cardiac damage. However, a number of studies have reported elevated cardiac troponin levels in asymptomatic, healthy subjects after endurance exercise (such as a marathon, prolonged cycling or prolonged walking). These observations indicate that elevated cardiac troponin levels can be the result of cardiac ischemia, and subsequent necrosis, but also may be related to strenuous exercise. In this paper, we present three different clinical cases of post-exercise elevations in cardiac troponins, each with a distinct clinical presentation. These case studies emphasize that a detailed assessment of all symptoms and a thorough patient-history are prerequisite for accurate interpretation of a positive cardiac troponin test following exercise.
Current Medical Chemistry
MH Eijsvogels, T., Shave, R., van Dijk, A., TE Hopman, M. and HJ Thijssen, D. (2011) 'Exercise-induced cardiac troponin release: real-life clinical confusion', Current medicinal chemistry, 18(23), pp.3457-3461
Dynodwr Gwrthrych Digidol (DOI)http://dx.doi.org/10.2174/092986711796642526
- Sport Research Groups 
Yn dangos eitemau sy’n perthyn drwy deitl, awdur, pwnc a chrynodeb.
Scharhag, Jurgen; George, Keith; Shave, Rob; Urhausen, Axel; Kindermann, Wilfried (2008)At present, the risk of myocardial damage by endurance exercise is under debate because of reports on exercise-associated increases in cardiac biomarkers troponin and B-type natriuretic peptide (BNP); these markers are ...
Shave, Rob; Ross, Peter; Low, David A.; George, Keith; Gaze, David (2010)It has been previously shown that cardiac troponin (cTn) is released in response to prolonged endurance exercise. The influence of short-duration high-intensity exercise upon the release of cTn is not known. We examined ...
Serrano-Ostariz, E.; Terreros-Blanco, J.L.; Legaz-Arrese, A.; George, Keith; Shave, Rob; Bocos-Terraz, P.; Izquierdo-Alvarez, S.; Bancalero, J.L.; Echavarri, J.M.; Quilez, J.; Carranza-Garcia, L.E.; Aragones, M.T. (2009)Numerous studies have observed cardiac biomarker release with prolonged exercise. Despite this, we are unsure as to the constituent aspects of any given exercise bout that may be important in promoting cardiac biomarker ...