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Exercise-induced cardiac troponin elevation: evidence, mechanisms, and implications

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Author
Shave, Rob
Baggish, Aaron
George, Keith
Wood, Malissa
Scharhag, Jurgen
Whyte, Greg
Gaze, David
Thompson, Paul D.
Date
2010
Type
Article
ISSN
0735-1097
Metadata
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Abstract
Regular physical exercise is recommended for the primary prevention of cardiovascular disease. Although the high prevalence of physical inactivity remains a formidable public health issue, participation in exercise programs and recreational sporting events, such as marathons and triathlons, is on the rise. Although regular exercise training reduces cardiovascular disease risk, recent studies have documented elevations in cardiac troponin (cTn) consistent with cardiac damage after bouts of exercise in apparently healthy individuals. At present, the prevalence, mechanism(s), and clinical significance of exercise-induced cTn release remains incompletely understood. This paper will review the biochemistry, prevalence, potential mechanisms, and management of patients with exercise-induced cTn elevations.
Journal/conference proceeding
Journal of the American College of Cardiology;
Citation
Shave, R., Baggish, A., George, K., Wood, M., Scharhag, J., Whyte, G., Gaze, D. and Thompson, P.D. (2010) 'Exercise-induced cardiac troponin elevation: evidence, mechanisms, and implications', Journal of the American College of Cardiology, 56(3), pp.169-176
URI
http://hdl.handle.net/10369/4391
DOI
http://dx.doi.org/10.1016/j.jacc.2010.03.037
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