Left ventricular myocardial strain and strain rates in sub-endocardial and sub-epicardial layers before and after a marathon
MetadataShow full item record
We assessed myocardial deformation in sub-endocardial and sub-epicardial layers of the left ventricle (LV) wall before and after running a marathon. Echocardiography scans were performed on 14 male, non-elite runners (mean ± SD; age 32 ± 10 years) who completed the 42.2-km London marathon. Para-sternal short axis and apical four-chamber views were recorded for off-line analysis. Peak longitudinal, radial and circumferential strains, peak systolic and early diastolic strain rates were recorded. Circumferential rotation in basal and apical LV scans was used to calculate torsion. Pre-race strain and strain rates were generally greater in the sub-endocardial layer of the LV wall. After race completion, a mixed pattern of change was observed with a reduction in sub-epicardial radial strain (32.6 ± 12.5 to 20.3 ± 9.6%; P < 0.01) and sub-endocardial circumferential strain (−26.9 ± 3.6 to −23.7 ± 4.1%; P < 0.01) at the apex. Rotation was not altered at either the apical or basal levels and thus torsion was not changed in either the sub-endocardium (6.72 ± 3.46° to 5.67 ± 4.98°) or the sub-epicardium (3.48 ± 2.68° to 3.01 ± 3.23°). Strain rates and rotation rates were only sporadically altered post-race. There are differences in deformation characteristics between the sub-endocardium and sub-epicardium at baseline, and the limited changes observed post-race were not specific to any region or depth of the LV wall.
European Journal of Applied Physiology;
Chan-Dewar, F., Oxborough, D., Shave, R., Gregson, W., Whyte, G. and George, K. (2010) 'Left ventricular myocardial strain and strain rates in sub-endocardial and sub-epicardial layers before and after a marathon', European Journal of Applied Physiology, 109 (6), pp.1191-1196
- Sport Research Groups 
Showing items related by title, author, subject and abstract.
The retrospective MIRU-VNTR typing Mycobacterium tuberculosis strains cultured from patients living in the Cardiff area between 2000 and 2010 Wong, Puwfun (Cardiff Metropolitan University, 2010)Tuberculosis is a major infectious disease worldwide and is the leading cause of death by a single infectious agent that can be controlled and treated. The World Health Organization aims to reduce the number of TB cases ...
Left ventricular wall segment motion after ultra-endurance exercise in humans assessed by myocardial speckle tracking George, Keith; Shave, Rob; Oxborough, David; Cable, Tim; Dawson, Ellen; Artis, Nigel; Gaze, David; Hew-Butler, Tamara; Sharwood, Karen; Noakes, Tim (2009)Aims Assessment of the left ventricular responses to prolonged exercise has been limited by technology available to assess cardiac tissue movement. Recently developed strain and strain rate imaging provide the unique ...
Cooper, Rose; Molan, P.C.; Harding, K.G. (Wiley, 2002)Aims: To determine the sensitivity to honey of Gram-positive cocci of clinical significance in wounds and demonstrate that inhibition is not exclusively due to osmotic effects. Methods and Results: Eighteen strains of ...