The impact of exercise duration and intensity on the release of cardiac biomarkers
MetadataShow full item record
Numerous studies have observed cardiac biomarker release with prolonged exercise. Despite this, we are unsure as to the constituent aspects of any given exercise bout that may be important in promoting cardiac biomarker release. This study examined the influence of exercise duration and intensity on the appearance of cardiac biomarkers. Twenty-one subjects ran for 45, 90 and 180 min at 85% and 95% of their individual anaerobic threshold on six different days randomized. Cardiac troponin I (cTnI) and N-terminal pro-brain natiuretic peptide (NT-proBNP) were assayed from blood samples collected before, 30 min and 3 h post-exercise. NT-proBNP was elevated after all exercise trials (range before: 21–32; range post: 38–67 ng/L). Peak post-exercise concentrations of NT-proBNP were associated with exercise duration (P=0.049), but not exercise intensity (P=0.451). cTnI was elevated after all exercise trials (range before: 0.007–0.011; range post: 0.008–0.021 μg/L). Peak post-exercise concentrations of cTnI were associated with exercise duration (P=0.003) and intensity (P=0.037). Data suggest that while both cTnI and NT-proBNP increased after all exercise trials, the mediating effect of duration influenced both NT-proBNP and cTnI while intensity influenced only cTnI.
Scandinavian Journal of Medicine and Science in Sports;
Serrano‐Ostáriz, E., Terreros‐Blanco, J.L., Legaz‐Arrese, A., George, K., Shave, R., Bocos‐Terraz, P., Izquierdo‐Álvarez, S., Bancalero, J.L., Echavarri, J.M., Quilez, J. and Aragonés, M.T. (2011) 'The impact of exercise duration and intensity on the release of cardiac biomarkers', Scandinavian Journal of Medicine & Science in Sports, 21(2), pp.244-249
First published online 17 November 2009
- Sport Research Groups 
Showing items related by title, author, subject and abstract.
Shave, Rob; Ross, Peter; Low, David A.; George, Keith; Gaze, David (2010)It has been previously shown that cardiac troponin (cTn) is released in response to prolonged endurance exercise. The influence of short-duration high-intensity exercise upon the release of cTn is not known. We examined ...
McGrigor, Craig (Cardiff Metropolitan University, 2014)Purpose: The purpose of this study was to determine the optimum intensity and duration to oxidise free fatty acids (FFA) during upper body arm ergometry over a 30-min exercise bout. Method: The sample population for this ...
Wightman, Amanada (Cardiff Metropolitan University, 2015)Aim: The present investigation aimed to explore the placebo effect of pre-exercise carbohydrate feeding via the ingestion a carbohydrate sports drink on short duration high intensity exercise. A secondary aim was to ...