Left ventricular wall segment motion after ultra-endurance exercise in humans assessed by myocardial speckle tracking
MetadataShow full item record
Aims Assessment of the left ventricular responses to prolonged exercise has been limited by technology available to assess cardiac tissue movement. Recently developed strain and strain rate imaging provide the unique opportunity to assess tissue deformation in all planes of motion. Methods and results Nineteen runners (mean ± SD age; 41 ± 9 years) were assessed prior to and within 60 min (34 ± 10 min) of race finish (Comrades Marathon, 89 km). Standard echocardiography assessed ejection fraction and the ratio of early to atrial ( E / A ) peak transmitral blood flow velocities. Myocardial speckle tracking determined segmental strain as well as systolic and diastolic strain rates in radial, circumferential, and longitudinal planes. Cardiac troponin T (cTnT) assessed cardiomyocyte insult. Ejection fraction (71 ± 5 to 64 ± 6%) and E / A (1.47 ± 0.35 to 1.25 ± 0.30) were reduced ( P < 0.05). Peak strain and peak systolic and diastolic strain rates were altered post-race in circumferential (e.g. peak strain reduced from 21.3 ± 2.4 to 17.3 ± 3.2%, P < 0.05) and radial planes. Some individual heterogeneity was observed between segments and planes of motion. A post-race elevation in cTnT (range 0.013–0.272 µg/L) in 5/12 runners did not differentiate changes in LV function. Conclusion Completion of the Comrades Marathon resulted in a depression in ejection fraction, E / A , as well as radial and circumferential strain and strain rates. Group data, however, masked some heterogeneity in cardiac function.
European Journal of Echocardiography;
George, K., Shave, R., Oxborough, D., Cable, T., Dawson, E., Artis, N., Gaze, D., Hew-Butler, T., Sharwood, K. and Noakes, T. (2009) 'Left ventricular wall segment motion after ultra-endurance exercise in humans assessed by myocardial speckle tracking', European Heart Journal-Cardiovascular Imaging, 10(2), pp.238-243
- Sport Research Groups 
Showing items related by title, author, subject and abstract.
A comparison of Doppler, tissue Doppler imaging, and strain rate imaging in the assessment of postexercise left ventricular function Shave, Rob; George, Keith; Whyte, Greg; Middleton, Natalie; Hart, Emma; Artis, Nigel; Oxborough, David (NRC Research Press, 2009)Left ventricular (LV) function is characterized by contraction in the longitudinal, radial, and circumferential planes. Previous studies of postexercise changes in LV function have assessed global indices of LV function. ...
Left ventricular myocardial strain and strain rates in sub-endocardial and sub-epicardial layers before and after a marathon Chan-Dewar, Fang; Oxborough, David; Shave, Rob; Gregson, Warren; Whyte, Greg; George, Keith (2010)We assessed myocardial deformation in sub-endocardial and sub-epicardial layers of the left ventricle (LV) wall before and after running a marathon. Echocardiography scans were performed on 14 male, non-elite runners (mean ...
Microbiological and observational analysis of cross contamination risks during domestic food preparation Redmond, Elizabeth; Griffith, Chris J.; Slader, J.; Humphrey, T.J. (Emerald Group Publishing Limited, 2004)The use of an observational approach in conjunction with isolation techniques for campylobacter and salmonella detection has facilitated a detailed evaluation of the risk of cross contamination during food preparation. ...