Exercise-associated increases in cardiac biomarkers
MetadataShow full item record
At present, the risk of myocardial damage by endurance exercise is under debate because of reports on exercise-associated increases in cardiac biomarkers troponin and B-type natriuretic peptide (BNP); these markers are typically elevated in patients with acute myocardial infarction and chronic heart failure, respectively. Exercise-associated elevations of cardiac biomarkers can be present in elite and in recreational athletes, especially after prolonged and strenuous endurance exercise bouts (e.g., marathon and ultratriathlon). However, in contrast to cardiac patients, it is still unclear if the exercise-associated appearance or increase in cardiac biomarkers in obviously healthy athletes represents clinically significant cardiac insult or is indeed part of the physiological response to endurance exercise. In addition, elevations in cardiac biomarkers in athletes after exercise may generate difficulties for clinicians in terms of differential diagnosis and may result in inappropriate consequences. Therefore, the aim of this article is to provide an overview of exercise-associated alterations of the cardiac biomarkers troponin T and I, ischemia-modified albumin, BNP, and its cleaved inactive fragment N-terminal pro BNP for the athlete, coach, scientist, and clinician.
Medicine & Science in Sports & Exercise
Scharhag, J., George, K., Shave, R., Urhausen, A. and Kindermann, W. (2008) 'Exercise-associated increases in cardiac biomarkers',Medicine & Science in Sports & Exercise, 40 (8), pp.1408-15
- Sport Research Groups 
Showing items related by title, author, subject and abstract.
Serrano-Ostariz, E.; Terreros-Blanco, J.L.; Legaz-Arrese, A.; George, Keith; Shave, Rob; Bocos-Terraz, P.; Izquierdo-Alvarez, S.; Bancalero, J.L.; Echavarri, J.M.; Quilez, J.; Carranza-Garcia, L.E.; Aragones, M.T. (2009)Numerous studies have observed cardiac biomarker release with prolonged exercise. Despite this, we are unsure as to the constituent aspects of any given exercise bout that may be important in promoting cardiac biomarker ...
Scott, Jessica M.; Esch, Ben T.; Shave, Rob; Warburton, Darren; Gaze, David; George, Keith (2009)Purposes: To comprehensively investigate the cardiovascular consequences of a 160-km ultramarathon using traditional echocardiography, speckle tracking imaging, cardiac biomarkers, and heart rate variability (HRV) and to ...
Cooke, Samuel; Samuel, T. Jake; Cooper, Stephen-Mark; Stöhr, Eric J. (Wiley, 2018-09-11)Despite increased stroke volume (SV), the‘athlete's heart’ has been proposed to have a similar left ventricular (LV) muscle function ‐ as represented by LV twist – compared with the untrained state. However, the underpinning ...