Longitudinal plane colour tissue-Doppler myocardial velocities and their association with left ventricular length, volume, and mass in humans
Batterham, Alan M.
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Aims We investigated the relationships between colour tissue-Doppler parameters of left ventricular (LV) function and indices of LV morphology. Methods and results LV length, end-diastolic volume, and mass were assessed in 40 healthy adult subjects. Further, colour tissue-Doppler scans assessed peak myocardial velocities during systole (S′) and early diastole (E′) as well as acceleration during isovolumic contraction (IVCa) at the mitral annulus. Non-linear allometric relationships ( Y = aXb ) were calculated to provide size exponents ( b ), with 95% confidence intervals, for tissue-Doppler variables ( Y ) and LV morphology parameters ( X ). The b exponents for LV length with Peaks S′ and E′ were not substantially different from unity ( b = 0.87 and 0.95, respectively, P > 0.05). Peak E′ was also associated with LV volume ( b = 0.39, r = 0.53, P < 0.05). IVCa was not related to any LV morphology parameter. Conclusion Peak S′ or E′ divided by LV length was confirmed as a valid size-independent scaling index. Conversely, IVCa is seemingly size independent.
European Journal of Echocardiography;
Batterham, A., Shave, R., Oxborough, D., Whyte, G. and George, K. (2008) 'Longitudinal plane colour tissue-Doppler myocardial velocities and their association with left ventricular length, volume, and mass in humans', European Heart Journal-Cardiovascular Imaging, 9 (4), pp. 542-546
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