Body composition and cardiovascular risk: Investigation of body adiposity asan independent determinant of arterial stiffness, central blood pressure and peripheral blood pressure measurements.
Cardiff Metropolitan University
MetadataShow full item record
Introduction: Cardiovascular Disease (CVD) is responsible for a large proportion of global morbidity and mortality each year and obesity is one of the factors implicated in increasing the risk of CVD. Research exploring the relationship between obesity and CVD risk factors has used a variety of different methodologies for measuring body fat and CVD risk factors and is mostly confined to older adults. This investigation studied the relationship, in young adults, between obesity and both arterial stiffening (measured as augmentation index (Alx)) and blood pressures (central and peripheral) using commonly available specified methods of measurement. Further analysis was performed on three commonly used assessors of body fat; Bioelectrical lmpedance (BEl), Body Mass Index (BMl) and Waist Circumference (WC) in order to obtain the most appropriate predictor of CVD risk. Methodology: A cohort of 24 healthy non-smoking participants (m=13, f--1 1) aged 19 – 30 years were recruited. In the study, height and weight measurements were recorded to calculate body mass lndex and waist circumference measurements were taken using an anthropometric measuring tape. Arm-leg bioelectrical impedance was used to measure body fat percentage (BF%). Peripheral blood pressure (PBP) was measured using a digital blood pressure monitor and both Alx and central blood pressure (CBP) were measured using Applanation Tonometry. Resu/fs: Regression Analysis (RA), using SPSS 17 statistical analysis software, showed a significant relationship between BF% and Alx (p=0.915, r=0.489), and a significant inverse relationship between BF% and peripheral systolic BP (p=0.025, r=-0.457) was observed. A gender-specific RA also found a significant relationship between BF% and Alx only in males (p= 0.019, r=0.636). Analysis of the methods of assessing body fat found significant relationships between BF% measured by BEI and Alx (p=0.015, r=0.489) and between WC and Alx (p=0.019, r=0.693). No significant association was found between BMI and Alx (p=0.087). Conclusion: Increased body fat percentage was significantly related to increased arterial stiffening, particularly in men, as well as a decreased peripheral systolic blood pressure. An analysis of methods of assessing body fat indicate that body fat percentage measured through both bioelectrical impedance and waist circumference are better and more accurate at predicting the development of cardiovascular disease, compared to body mass index.
BSc (Hons) Sport Biomedicine and Nutrition
Showing items related by title, author, subject and abstract.
The relationship between waist circumference and vascular haemodynamics (such as arterial a stiffness and blood pressure) post glucose ingestion Woodland, Ben (Cardiff Metropolitan University, 2011)Purpose: The present study was set out to investigate the impact of acute hyperglycaemia on endothelialfunction and haemodynamic parameters in 20 healthy young adults, free from disease, in relation to waist circumferenc ...
Central Pressure: Variability and Impact of Cardiovascular Risk Factors: The Anglo-Cardiff Collaborative Trial II McEniery, Carmel; McDonnell, Barry; Munnery, Margaret; Wallace, Sharon; Rowe, Chloe; Cockcroft, John R.; Wilkinson, Ian (American Heart Association, 2008)Pulse pressure varies throughout the arterial tree, resulting in a gradient between central and peripheral pressure. Factors such as age, heart rate, and height influence this gradient. However, the relative impact of ...
Lane, Sophie (Cardiff Metropolitan University, 2015)Introduction: High blood pressure has been identified to largely contribute to cardiovascular disease. Regular exercise has been prescribed by medical organisations as a strategy to treat and prevent high blood pressure. ...