Visfatin/Nampt induces telomere damage and senescence in human endothelial cells
Sanchez-Ferrer, Carlos F.
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The adipose tissue is an active endocrine organ that releases a wide array of substances, globally termed adipokines. Among these, visfatin is a multifaceted molecule, structurally identical to the extracellular form of nicotinamide phosphoribosyltransferase (Nampt), which enzymatically converts nicotinamide into nicotinamide mononucleotide (NMN) and whose circulating levels are enhanced in metabolic disorders
International Journal of Cardiology
Villalobos, L.A., Uryga, A., Romacho, T., Leivas, A., Sánchez-Ferrer, C.F., Erusalimsky, J.D. and Peiró, C. (2014) 'Visfatin/Nampt induces telomere damage and senescence in human endothelial cells', International Journal of Cardiology, 175(3), pp.573-575.
Open access journal; This article was published in International Journal of Cardiology on 17th May 2014 (online), available at http://dx.doi.org/10.1016/j.ijcard.2014.05.028