Simulated games activity versus continuous running exercise: a novel comparison of the glycaemic and metabolic responses in T1DM patients
Campbell, Matthew. D.
West, Daniel J.
Bain, Stephen C.
Kingsley, Michael I.C.
Stephens, Jeffery W.
Bracken, Richard M.
Wiley Online Library
MetadataShow full item record
AIM: To compare the glycaemic and metabolic responses to simulated intermittent games activity and continuous running exercise in T1DM. METHODS: Nine patients (7 male, 2 female; 354 years; HbA1c 8.10.2% / 652 mmol.mol-1) treated on a basal-bolus regimen completed two main trials, a continuous treadmill run (CON) or an intermittent running protocol (INT). Patients arrived to the laboratory fasted at ~08:00 h, replicating their usual pre-exercise meal and administering a 50% reduced dose of rapid-acting insulin before exercising. Blood glucose (BG), K+, Na++, pH, triglycerides, serum cortisol and NEFA were measured at baseline and for 60 minutes post-exercise. Interstitial glucose was measured for a further 23 hours under free-living conditions. RESULTS: Following exercise, BG declined under both conditions but was less under INT (INT -1.1±1.4 vs. CON -5.3±0.4 mmol.l-1, p=0.037) meaning more patients experienced hypoglycaemia (BG≤3.5mmol.l-1; CON n=3 vs. INT n=2) but less hyperglycaemia (BG≥10.9 mmol.l-1; CON n=0 vs. INT n=6) under CON. Blood lactate was significantly greater, and pH lower, with a temporal delay in K+ under INT (p<0.05). No conditional differences were observed in other measures during this time, or in interstitial glucose concentrations during the remaining 23 hours after exercise. CONCLUSIONS: Simulated games activity carries a lower risk of early, but not late-onset hypoglycaemia than continuous running exercise in T1DM
Scandinavian Journal of Medicine & Science in Sports
Campbell, M. D., West, D. J., Bain, S. C., Kingsley, M. I. C., Foley, P., Kilduff, L., Turner, D., Gray, B., Stephens, J. W. and Bracken, R. M. (2015) 'Simulated games activity vs continuous running exercise: a novel comparison of the glycemic and metabolic responses in T1DM patients', Scandinavian Journal of Medicine & Science in Sports, 25 (2), pp. 216–222.
This article was published in Scandinavian Journal of Medicine & Science in Sports on 4 March 2014 (online), available at http://dx.doi.org/10.1111/sms.12192
Showing items related by title, author, subject and abstract.
Impaired myocardial function does not explain reduced left ventricular filling and stroke volume at rest or during exercise at high altitude Stembridge, Mike; Ainslie, Philip; Hughes, Michael G.; Stöhr, Eric J.; Cotter, James D.; Tymko, Michael M.; Day, Trevor A.; Bakker, Akke; Shave, Rob (American Physiological Society, 2015-11-15)Impaired myocardial systolic contraction and diastolic relaxation have been suggested as possible mechanisms contributing to the decreased stroke volume (SV) observed at high altitude (HA). To determine whether intrinsic ...
ASTHMATIC ATHLETES AND THE IMPACT OF SALBUTAMOL AND A HIGH INTENSITY INTERVAL WARM-UP ON THE BRONCHOCONSTRICTOR RESPONSE TO EXERCISE Newton, Kitty (Cardiff Metropolitan University, 2015)Aim: The main aim of this thesis was to investigate the efficacy of high-intensity interval warm-up on the severity of Exercise Induced Bronchoconstriction (EIB), compared to an inhaled short-acting beta2-agonist and a ...
Effects of exercise intensity on clot microstructure and mechanical properties in healthy individuals. Davies, Nia; Llwyd, L; Brugniaux, J.V.; Davies, G.R.; Marley, C.J.; Hodson, D; Lawrence, M.J.; D'Silva, L.A.; Morris, Keith; Williams, P.R.; Bailey, D.M.; Evans, P.A. (Elsevier, 2016-07)Background Exercise is well established to lead to exercise-induced hypercoagulability, as demonstrated by kinetic coagulation markers. It remains unclear as to whether exercise-induces changes lead in clot development ...