Should an increase in cerebral neurochemicals following head kicks in full contact karate influence return to play?
Evans, P. J.
MetadataShow full item record
Background: Cerebral neurochemicals are markers of traumatic brain injury (TBI). Objectives: The aim of the study was to determine whether kicks to the head (KTH) in full contact karate significantly increased serum concentrations of protein S-100B, and neurone specific enolase (NSE). Kicks to the body (KTB) were also quantified to asses muscle tissue injury. Muscle damage was assessed by analysis of serum total creatine kinase (CK). Methods: Twenty four full contact karate practitioners were observed and filmed during actual competition and divided into two main groups post event: (1): Kicks to the head and body group (KTH) n=12, mean ± SD, age 30.4 ± 6.7 years; height 1.74 ± 0.1 metres; weight 79.1 ± 2.1 kg. 2): Kicks to the body group (KTB) n=12, mean ± SD, age 28.2 ± 6.5 years; height 1.75 ± 0.1 metres; weight 79.2 ± 1.7 kg. The KTH group received direct kicks to the head, while group KTB received kicks and punches to the body. Blood samples were taken before and immediately post-combat for analysis of serum S-100B, NSE, CK and cardiac troponin. Results: Significant increases in serum concentrations of S-100B (0.12 ± 0.17 vs 0.37 ± 0.26, µg.L-1) and NSE (11.8 ± 4.1 vs 20.2 ± 9.1 ng.ml-1) were encountered after combat in the KTH group and CK (123 ± 53 vs 184 ± 103 U.L-1) in the KTB group (all P<0.05). Conclusions: Head kicks in full contact karate cause elevation of neurochemical markers associated with damaged brain tissue. The severity of injury is related to the early post-traumatic release of protein S-100B and NSE. The early kinetics and appearance post injury can reflect intracranial pathology, and suggest S-100B and NSE are extremely sensitive prognostic markers of TBI.
International Journal of Immunopathology and Pharmacology
Graham, M.R., Pates, J., Davies, B., Cooper, S.M., Bhattacharya, K., Evans, P.J. and Baker, J.S., (2015) 'Should an increase in cerebral neurochemicals following head kicks in full contact karate influence return to play?', International Journal of Immunopathology and Pharmacology, 28(4) p.0394632015577045.
This article was published in International Journal of Immunopathology and Pharmacology on 26 March 2015 (online), available at http://dx.doi.org/10.1177/0394632015577045
- Sport Research Groups 
Showing items related by title, author, subject and abstract.
Rowley, Samantha (University of Wales Institute Cardiff, 2010)Background: The concurrent increase in food portion sizes and obesity levels suggests a need for increased public awareness of appropriate portions. Recent research has investigated the potential for quantitative guidance ...
Functional changes in people with different hearing status and experiences of using Chinese sign language: An fMRI study Qiang, Li; Xia, Shuang; Zhao, Fei (Elsevier, 2014-05-27)The purpose of this study was to assess functional changes in the cerebral cortex in people with different sign language experience and hearing status whilst observing and imitating Chinese Sign Language (CSL) using ...
Oxborough, D.; Heemels, A.; Somauroo, J.; McClean, G.; Mistry, P.; Lord, Rachel; Utomi, V.; Jones, N.; Thijssen, D.; Sharma, S.; Osborne, R. (Springer, 2016-05-21)We propose a novel ultrasound approach with the primary aim of establishing the temporal relationship of structure and function in athletes of varying sporting demographics. 92 male athletes were studied [Group IA, (low ...