Nanoparticle technology to deliver effective antimicrobials

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Author
Maddocks, Sarah
Barbour, Michele
Collins, Andrew
Date
2015Type
Article
Publisher
Science Publications
ISSN
1948-982X
1948-9838 (ESSN)
Metadata
Show full item recordAbstract
Bacterial resistance to antimicrobials emerged only a few years after the commercial availability of antibiotics. Nanotechnology offers a means by which new antimicrobials can be developed, or the lifespan of current antimicrobials can be extended. Nanoparticles are loosely defined as particles with at least one dimension smaller than 100 nm; their specific surface area, chemical and biological activity can be tuned for a desired application. As such they have become attractive within a variety of fields including medicine and, in particular, antimicrobial therapy. Nanoparticles with specific surface chemistry and size can intimately interact with the microbial surface mediating an antimicrobial effect that does not necessarily rely on the release of chemically active components. Moreover, nanoparticles can be incorporated into polymers or applied as coatings on surfaces, such as indwelling medical devices, making them extremely versatile; combined with a slow rate of release this means that they offer sustained antimicrobial activity.
Journal/conference proceeding
American Journal of Microbiology
Citation
Maddocks,S. E., Barbour, M. E. and Collins, A. M. (2014) 'Nanoparticle technology to deliver effective antimicrobials', American Journal of Microbiology, 5 (2), pp. 35-36.
Description
This article was published in American Journal of Microbiology in 2014, available open access at http://dx.doi.org/10.3844/ajmsp.2014.35.36
Rights
Creative Commons Attribution LicenseCollections
Except where otherwise noted, this item's license is described as Creative Commons Attribution License
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