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dc.contributor.authorNollmann, Friederike I.
dc.contributor.authorHeinrich, Antje K.
dc.contributor.authorBrachmann, Alexander L.
dc.contributor.authorMorisseau, Christophe
dc.contributor.authorMukherjee, Krishnendu
dc.contributor.authorCasanova-Torres, Angel M.
dc.contributor.authorStrobl, Frederic
dc.contributor.authorKleinhans, David
dc.contributor.authorKinksi, Sebastian
dc.contributor.authorSchultz, Katharina
dc.contributor.authorBeeton, Michael L.
dc.contributor.authorKaiser, Marcel
dc.contributor.authorChu, Ya-Yun
dc.contributor.authorPhan Ke, L.
dc.contributor.authorThanwisai, Aunchalee
dc.contributor.authorBozhüyük, Kenan A.J.
dc.contributor.authorChantratita, Narisara
dc.contributor.authorGötz, Fredrich
dc.contributor.authorWaterfield, Nick R.
dc.contributor.authorVilcinskas, Andreas
dc.contributor.authorStelzer, Ernst H.K.
dc.contributor.authorGoodrich-Blair, Heidi
dc.contributor.authorHammock, Bruce D.
dc.contributor.authorBode, Helge B.
dc.date.accessioned2016-07-14T11:46:32Z
dc.date.available2016-07-14T11:46:32Z
dc.date.issued2015-03-16
dc.identifier.citationNollmann, F. I., Heinrich, A. K., Brachmann, A. O., Morisseau, C., Mukherjee, K., Casanova-Torres, Á. M., Strobl, F., Kleinhans, D., Kinski, S., Schultz, K., Beeton, M. L., Kaiser, M., Chu, Y.-Y., Phan Ke, L., Thanwisai, A., Bozhüyük, K. A. J., Chantratita, N., Götz, F., Waterfield, N. R., Vilcinskas, A., Stelzer, E. H. K., Goodrich-Blair, H., Hammock, B. D. and Bode, H. B. (2015), 'A Photorhabdus natural product inhibits insect juvenile hormone Epoxide Hydrolase', ChemBioChem, 16 (5), pp.766–771.en_US
dc.identifier.issn1439-4227
dc.identifier.issn1439-7633 (ESSN)
dc.identifier.urihttp://dx.doi.org/10.1002/cbic.201402650
dc.identifier.urihttp://hdl.handle.net/10369/7972
dc.descriptionThis article was published in ChemBioChem on 25 February 2015 (online), available open access at http://dx.doi.org/10.1002/cbic.201402650en_US
dc.description.abstractSimple urea compounds (“phurealipids”) have been identified from the entomopathogenic bacterium Photorhabdus luminescens, and their biosynthesis was elucidated. Very similar analogues of these compounds have been previously developed as inhibitors of juvenile hormone epoxide hydrolase (JHEH), a key enzyme in insect development and growth. Phurealipids also inhibit JHEH, and therefore phurealipids might contribute to bacterial virulence.en_US
dc.language.isoenen_US
dc.publisherWiley Online Libraryen_US
dc.relation.ispartofseriesChemBioChem;
dc.rightsCreative Commons Attribution License
dc.rights.urihttps://creativecommons.org/licenses/by/3.0/
dc.subjectbiosynthesisen_US
dc.subjectentomopathogenic bacteriaen_US
dc.subjectjuvenile hormone epoxide hydrolase inhibitoren_US
dc.subjectnatural productsen_US
dc.subjectPhotorhabdusen_US
dc.titleA Photorhabdus natural product inhibits insect juvenile hormone Epoxide Hydrolaseen_US
dc.typeArticleen_US
dc.date.dateAccepted2014-11-07


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