The effect of training status on the associations between aortic reservoir pressure and left ventricular untwisting rate.
Samuel, Thomas Jake
MetadataShow full item record
Athletic training status is known to influence cardiac function, although the mechanisms causing the changes are currently unknown. It is known that changes in arterial function can lead to cardiac adaptation and that trained individuals have a greater arterial desaturation in conditions of reduced oxygen availability. To help explain the influence of training status on cardiac function, this study aimed to investigate the associations between peak left ventricular (LV) untwisting rate and aortic reservoir pressure (RP) in normoxic and hypoxic conditions. The LV mechanics and aortic haemodynamics of 13 untrained males and 8 highly trained males (VO2peak: 36.4 ± 6.4 vs. 46.2 ± 6.1 ml.min.Kg-1) were assessed at rest and during sub-maximal exercise at 30, 40 and 50% of peak power output in normoxic (FiO2 = ~20.9%) and hypoxic conditions (FiO2 = ~12.0%). Trained individuals had a significantly higher aortic RP integral, a consistently lower sphericity index (repeated measures ANOVA: all P ≤ 0.05), and similar LV untwisting rates during both normoxic and hypoxic sub-maximal exercise (P > 0.05). Additionally, LV untwisting rate was significantly associated with aortic RP in trained individuals in normoxia and untrained individuals in hypoxia only (r2 = 0.37 and 0.12, respectively; both P ≤ 0.01). In conclusion, training status impacts on the associations between LV untwisting rate and aortic haemodynamic function, and the increased aortic reservoir function seen in trained individuals may play a role in facilitating a greater distribution of blood flow to the coronary arteries.
- Masters Degrees (Sport) 
Showing items related by title, author, subject and abstract.
Cooke, Samuel (2016-03-16)Introduction: Left ventricular (LV) twist and untwisting rate (LV twist mechanics) play a crucial role during myocardial deformation. It is suggested that exercise training alters resting LV twist mechanics. However, it ...
Impaired myocardial function does not explain reduced left ventricular filling and stroke volume at rest or during exercise at high altitude Stembridge, Mike; Ainslie, Philip; Hughes, Michael G.; Stöhr, Eric J.; Cotter, James D.; Tymko, Michael M.; Day, Trevor A.; Bakker, Akke; Shave, Rob (American Physiological Society, 2015-11-15)Impaired myocardial systolic contraction and diastolic relaxation have been suggested as possible mechanisms contributing to the decreased stroke volume (SV) observed at high altitude (HA). To determine whether intrinsic ...
An Assessment of the Relationship Between Regional Mechanical Myocardial Function and the Electrocardiogram Foxwell, Ben (Cardiff Metropolitan University, 2014)It has previously been established that the left ventricle (LV) of the myocardium counter-rotates around its long axis on contraction. The apex and base rotate in opposite directions to create a wringing motion, resulting ...