Chemical characterisation and the anti-inflammatory, anti-angiogenic and antibacterial properties of date fruit (Phoenix dactylifera L.)
MetadataShow full item record
Ethnopharmacological relevance: Date fruit, Phoenix dactylifera L. has traditionally been used as a medicine in many cultures for the treatment of a range of ailments such as stomach and intestinal disorders, fever, oedema, bronchitis and wound healing. Aim of the review: The present review aims to summarise the traditional use and application of Phoenix dactylifera date fruit in different ethnomedical systems, additionally the botany and phytochemistry are identified. Critical evaluation of in vitro and in vitro studies examining date fruit in relation to anti-inflammatory, anti-angiogenic and antimicrobial activities are outlined. Key Findings: The ethnomedical use of Phoenix dactylifera in the treatment of inflammatory disease has been previously identified and reported. Furthermore, date fruit and date fruit co-products such as date syrup are rich sources of polyphenols, anthocyanins, sterols and carotenoids. In vitro studies have demonstrated that date fruit exhibits antibacterial, anti-inflammatory and anti-angiogenic activity. The recent interest in the identification of the numerous health benefits of dates using in vitro and in vivo studies have confirmed that date fruit and date syrup have beneficial health effects that can be attributed to the presence of natural bioactive compounds. Conclusions: Date fruit and date syrup have therapeutic properties, which have the potential to be beneficial to health. However, more investigations are needed to quantify and validate these effects.
Journal of Ethnopharmacology;
Taleb, H., Maddocks, S.E., Morris, R.K. and Kanekanian, A.D. (2016) 'Chemical characterisation and the anti-inflammatory, anti-angiogenic and antibacterial properties of date fruit (Phoenix dactylifera L.)', Journal of Ethnopharmacology, 194, pp. 457-468
This article was published in Journal of Ethnopharmacology on 10 October 2016, available at http://dx.doi.org/10.1016/j.jep.2016.10.032
Cardiff Metropolitan University (Grant ID: Cardiff Metropolian (Internal))
Showing items related by title, author, subject and abstract.
Date syrup derived polyphenols attenuate angiogenic responses and exhibits anti-inflammatory activity mediated by VEGF and COX-2 expression in endothelial cells Taleb, Hajer; Morris, Keith; Withycombe, Cathryn; Maddocks, Sarah; Kanekanian, Ara (Science Direct, 2016-02-22)Bioactive components such as polyphenols, present in many plants, are purported to have anti-inflammatory and antiangiogenic properties. Date syrup, produced from date fruit of the date palm tree, has traditionally been ...
Wilson, Emily (Cardiff Metropolitan University, 2017-06-01)Colon cancer is the fourth most commonly diagnosed cancer within the UK, and in 2014 there were 41,300 people diagnosed with the disease . With cancer statistics on the increase it would be beneficial for both patients ...
The In-vitro effect of Apigenin on Vascular Endothelial Growth Factor and Interleukin-8 production within Caco-2 cells. Amartey, Jason Otu (Cardiff Metropolitan University, 2017-06-01)Background It has been stated that inflammation is the ‘foundation’ of many diseases and disorders. In recent times, there has been a growing interest in the potential of using natural chemicals such as flavonoids as ...