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Chemical characterisation and the anti-inflammatory, anti-angiogenic and antibacterial properties of date fruit (Phoenix dactylifera L.)

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Author
Taleb, Hajer
Maddocks, Sarah
Morris, Keith
Kanekanian, Ara
Date
2016-10-10
Acceptance date
2016-10-07
Type
Article
Publisher
Elsevier
ISSN
0378-8741
Metadata
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Abstract
Ethnopharmacological relevance: Date fruit, Phoenix dactylifera L. has traditionally been used as a medicine in many cultures for the treatment of a range of ailments such as stomach and intestinal disorders, fever, oedema, bronchitis and wound healing. Aim of the review: The present review aims to summarise the traditional use and application of Phoenix dactylifera date fruit in different ethnomedical systems, additionally the botany and phytochemistry are identified. Critical evaluation of in vitro and in vitro studies examining date fruit in relation to anti-inflammatory, anti-angiogenic and antimicrobial activities are outlined. Key Findings: The ethnomedical use of Phoenix dactylifera in the treatment of inflammatory disease has been previously identified and reported. Furthermore, date fruit and date fruit co-products such as date syrup are rich sources of polyphenols, anthocyanins, sterols and carotenoids. In vitro studies have demonstrated that date fruit exhibits antibacterial, anti-inflammatory and anti-angiogenic activity. The recent interest in the identification of the numerous health benefits of dates using in vitro and in vivo studies have confirmed that date fruit and date syrup have beneficial health effects that can be attributed to the presence of natural bioactive compounds. Conclusions: Date fruit and date syrup have therapeutic properties, which have the potential to be beneficial to health. However, more investigations are needed to quantify and validate these effects.
Journal/conference proceeding
Journal of Ethnopharmacology;
Citation
Taleb, H., Maddocks, S.E., Morris, R.K. and Kanekanian, A.D. (2016) 'Chemical characterisation and the anti-inflammatory, anti-angiogenic and antibacterial properties of date fruit (Phoenix dactylifera L.)', Journal of Ethnopharmacology, 194, pp. 457-468
URI
http://hdl.handle.net/10369/8151
DOI
http://dx.doi.org/10.1016/j.jep.2016.10.032
Description
This article was published in Journal of Ethnopharmacology on 10 October 2016, available at http://dx.doi.org/10.1016/j.jep.2016.10.032
Rights
https://creativecommons.org/licenses/by-nc-nd/3.0/
Sponsorship
Cardiff Metropolitan University (Grant ID: Cardiff Metropolian (Internal))
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