Binding of two bacterial biofilms to dialkyl carbamoyl chloride (DACC)-coated dressings in vitro
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Objective: To date only planktonic bacteria have been shown to bind irreversibly to dialkyl carbamoyl chloride (DACC)-coated Cutimed Sorbact dressings. Therefore, this study was designed to determine whether bacterial biofilm bound to the DACC-coated dressing in vitro. Method: Samples of DACC-coated dressings and uncoated control dressings (supplied by BSN medical Ltd, Hull) were placed in contact with plastic coverslips on which biofilms of either Pseudomonas aeruginosa or methicillin-resistant Staphylococcus aureus (MRSA) had been cultivated for 24 hours. Dressing samples were examined by scanning electron microscopy to detect the presence of biofilm. Results: Pseudomonas aeruginosa biofilm bound avidly to both DACC-coated and uncoated dressing samples. MRSA bound more extensively to DACC-coated dressings than to uncoated samples. Conclusion: Biofilms of two different test bacteria bound to dressings in vitro with the DACC-coating on the dressings enhancing the binding of MRSA biofilm. Declaration of interest: This study was supported by BSN medical Ltd (Hull). The company had no influence on the experimental design or the interpretation of the results.
Journal of Wound Care;
Cooper, R. and Jenkins, L. (2016) 'Binding of two bacterial biofilms to dialkyl carbamoyl chloride (DACC)-coated dressings in vitro', Journal of Wound Care, 25(2), pp.76-82
This article was published in Journal of Wound Care on 15 February 2016 (online), available at http://dx.doi.org/10.12968/jowc.2016.25.2.76
Cardiff Metropolitan University (Grant ID: Cardiff Metropolian (Internal))
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