An Investigation into the Accuracy of the Mobil-O-graph in Measuring Aortic Pulse Wave Velocity Compared to the SphygmoCor
Keane, Joseph William
Cardiff Metropolitan University
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Since aortic stiffness has emerged as an independent predictor of cardiovascular morbidity and mortality. Non-invasive measurement of aortic pulse wave velocity (aPWV) is of great importance in the management and treatment of cardiovascular disease. We therefore validated the Mobil-O-Graph against the SphygmoCor device, which is widely known and accepted as the gold standard device for non-invasive estimation of aPWV. For each participant, we compared two readings of aPWV recorded by the Mobil-O-graph and SphygmoCor devices. Thirty-seven participants (mean age 47.9 ± 24.6) were recruited for this study. Differences between central blood pressure values of both devices were calculated for each measurement. The mean age of the study group was 47.9 years (IQR: 20-87 years, 26 females, 11 males). A very strong correlation was found between Mobil-O-graph and SphygmoCor devices (r = 0.770, p < 0.001). The mean PWV for the Mobil-O-graph was 8.5 ± 3.2 and the mean PWV for the SphygmoCor was 7.8 ± 3, which wasn’t statistically significant (p = 0.350). The Bland-Altman showed an estimated difference of 0.684 with two standard deviations above (5.864) and below (-4.496). Oscillometric non-invasive estimation via the Mobil-O-Graph overestimates aPWV in comparison to the well-established SphygmoCor applanation tonometry device. Although results do show acceptable agreement, some degree of caution is needed to use interchangeably.
BSc (Hons) Sports Biomedicine and Nutrition
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