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dc.contributor.authorAtencia, Rebeca
dc.contributor.authorStöhr, Eric J.
dc.contributor.authorDrane, Aimee L.
dc.contributor.authorStembridge, Mike
dc.contributor.authorHowatson, Glyn
dc.contributor.authordel Rio, Pablo Rodriguez Lopez
dc.contributor.authorFeltrer, Yedra
dc.contributor.authorTafon, Babila
dc.contributor.authorRedrobe, Sharon
dc.contributor.authorPeck, Bruce
dc.contributor.authorEng, Jaclyn
dc.contributor.authorUnwin, Steve
dc.contributor.authorSanchez, Carols R.
dc.contributor.authorShave, Rob
dc.date.accessioned2017-11-30T10:53:17Z
dc.date.available2017-11-30T10:53:17Z
dc.date.issued2017-09-01
dc.identifier.citationAtencia, R., Stohr, E.J., Drane, A.L., Stembridge, M., Howatson, G., Lopez del Rio, P.R., Feltrer, Y., Tafon, B., Redrobe, S., Peck, B., Eng, J., Unwin, C.R., Sanchez, C.R. and Shave, R.E. (2017) 'Heart rate and indirect blood pressure responses to four different field anesthetic protocols in wild born captive chimpanzees (pan troglodytes)', Journal of Zoo and Wildlife Medicine, 48(3), pp.636-644en_US
dc.identifier.issn1937-2825 (ESSN)
dc.identifier.urihttp://hdl.handle.net/10369/9180
dc.descriptionThis article was published in Journal of Zoo and Wildlife Medicine on 01 September 2017 (online), available at https://doi.org/10.1638/2016-0181.1en_US
dc.descriptionClosed deposit
dc.description.abstractLimited data are available on hemodynamic responses to anesthetic protocols in wild-born chimpanzees (Pan troglodytes). Accordingly, this study characterized the heart rate (HR) and blood pressure responses to four anesthetic protocols in 176 clinically healthy, wild-born chimpanzees undergoing routine health assessments. Animals were anesthetized with medetomidine–ketamine (MK) (n = 101), tiletamine–zolazepam (TZ) (n = 30), tiletamine–zolazepam–medetomidine (TZM) (n = 24), or medetomidine–ketamine (maintained with isoflurane) (MKI) (n = 21). During each procedure, HR, systolic blood pressure (SBP), and diastolic blood pressure (DBP) were regularly recorded. Data were grouped according to anesthetic protocol, and mean HR, SBP, and DBP were calculated. Differences between mean HR, SBP, and DBP for each anesthetic protocol were assessed using the Kruskall–Wallis test and a Dunn multiple comparisons post hoc analysis. To assess the hemodynamic time course response to each anesthetic protocol, group mean data (±95% confidence interval [CI]) were plotted against time postanesthetic induction. Mean HR (beats/min [CI]) was significantly higher in TZ (86 [80–92]) compared to MKI (69 [61–78]) and MK (62 [60–64]) and in TZM (73 [68–78]) compared to MK. The average SBP and DBP values (mm Hg [CI]) were significantly higher in MK (130 [126–134] and 94 [91–97]) compared to TZ (104 [96–112] and 58 [53–93]) and MKI (113 [103–123] and 78 [69–87]) and in TZM (128 [120–135] and 88 [83–93]) compared to TZ. Time course data were markedly different between protocols, with MKI showing the greatest decline over time. Both the anesthetic protocol adopted and the timing of measurement after injection influence hemodynamic recordings in wild-born chimpanzees and need to be considered when monitoring or assessing cardiovascular health.en_US
dc.language.isoenen_US
dc.publisherBioOneen_US
dc.relation.ispartofseriesJournal of Zoo and Wildlife Medicine;
dc.subjectheart rateen_US
dc.subjectblood pressureen_US
dc.subjectchimpanzeesen_US
dc.subjectwild born captive chimpsen_US
dc.titleHeart rate and indirect blood pressure responses to four different field anesthetic protocols in wild born captive chimpanzees (pan troglodytes)en_US
dc.typeArticleen_US
dc.identifier.doihttps://doi.org/10.1638/2016-0181.1
dcterms.dateAccepted2017-06-04
rioxxterms.versionAMen_US
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserveden_US
rioxxterms.licenseref.startdate2017-11-30
dc.refexceptionThe publication concerned actively disallows open-access deposit in a repository, and was the most appropriate publication for the output
rioxxterms.freetoread.startdate2100-01-01


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