Logistic Regression Analysis of Factors Influencing the Effectiveness of Intensive Sound Masking Therapy in Patients with Tinnitus
BMJ Publishing Group
MetadataShow full item record
Objectives: To investigate factors influencing the effectiveness intensive sound masking therapy on tinnitus using Logistic Regression Analysis. Design: The study used a retrospective cross-section analysis. Participants: 102 patients with tinnitus were recruited at the Sun Yat-sen Memorial Hospital of Sun Yat-sen University, China. Intervention: Intensive sound masking therapy was used as an intervention approach for patients with tinnitus. Primary and secondary outcome measures: participants underwent audiological investigations and tinnitus pitch and loudness matching measurements, followed by intensive sound masking therapy. The Tinnitus Handicap Inventory (THI) was used as the outcome measure pre- and post-treatment. Multivariate logistic regression was performed to investigate the association of demographic and audiological factors with effective therapy. Results: According to the THI score changes pre-and post-sound masking intervention, fifty-one participants were categorised into an effective group, the remaining 51 participants were placed in a non-effective group. Those in the effective group were significantly younger than those in the non-effective group (p=0.012). Significantly more participants had flat audiogram configurations in the effective group (p=0.04). Multivariable logistic regression analysis showed that age (OR=0.96, 95% CI: 0.93, 0.99, p=0.007), audiometric configuration (p=0.027) and THI score pre-treatment (OR=1.04, 95% CI: 1.02, 1.07, p<0.001) were significantly associated with therapeutic effectiveness. Further analysis showed that patients with flat audiometric configurations were 5.45 times more likely to respond to intervention than those with high-frequency steeply sloping audiograms (OR=5.45, 95% CI: 1.67, 17.86, p=0.005). Conclusion: Audiometric configuration, age and THI scores appear to be predictive for the effectiveness of sound masking treatment. Gender, tinnitus characteristics and hearing threshold measures seem not to be related to treatment effectiveness. Further randomized control study is needed to provide further evidence of the effectiveness of prognostic factors in tinnitus interventions.
Cai YX,, Zhou Q, Yang HD, Jiang JJ, Zhao F, Huang XY, Mo HJ, Chen XT, Xiong H, Chen SJ, Zhang XY, Zheng YQ (2017) 'Logistic Regression Analysis of Factors Influencing the Effectiveness of Intensive Sound Masking Therapy in Patients with Tinnitus', BMJ Open, 7(11):e018050.
This article was published in BMJ Open on 01 November 2017, available open access online at http://dx.doi.org/10.1136/bmjopen-2017-018050
Cardiff Metropolitan University (Grant ID: Cardiff Metropolian (Internal))
Showing items related by title, author, subject and abstract.
The Acceptability and Influencing Factors of an Internet-Based Tinnitus Multivariate Integrated Sound Therapy for Patients With Tinnitus Lan, Tianxiang; Zhao, Fei; Xiong, Binbin (Sage, 2020-12-01)Objective: To explore the acceptability and influencing factors of an Internet-based Tinnitus Multivariate Integrated Sound Therapy (iT-MIST). The individually tailored sound therapy used narrowband noise centered on the ...
The Association Between Effectiveness of Tinnitus Intervention and Cognitive Function—A Systematic Review Lan, Tianxiang; Cao, Zuwei; Zhao, Fei; Perham, Nick (Frontiers Media, 2021-01-06)Tinnitus refers to the perception of sound in the absence of an external stimulus. This can be problematic and can lead to health problems in some sufferers, including effects on cognitive functions such as attention and ...
The Long‐term Effectiveness of Tinnitus Multivariate Integrated Sound Therapy (T‐MIST) in 148 tinnitus patients with normal hearing thresholds: Our initial experience Zhao, Yuanxin; Zhao, Fei; El Refaie, Amr; Wang, Bochen; Chen, Danping; Chen, Kangsong; Lan, Tianxiang (Wiley, 2019-09-04)1. This preliminary study provides a combined sound therapeutic strategy (called T-MIST) for the management of tinnitus patients with normal hearing thresholds. It takes into account individual tinnitus characteristics and ...