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dc.contributor.authorCarter, Howard
dc.contributor.authorSpence, Angela
dc.contributor.authorPugh, Christopher J. A.
dc.contributor.authorAinslie, Philip N.
dc.contributor.authorNaylor, Louise
dc.contributor.authorGreen, Daniel
dc.identifier.citationCarter, H., Spence, A., Pugh, C., Ainslie, P., Naylor, L., and Green, D. (2014) 'Cardiovascular responses to water immersion in humans: Impact on cerebral perfusion', American Journal of Physiology - Regulatory, Integrative and Comparative Physiology, 306(9), pp. R636-R640.en_US
dc.descriptionCopy not available from this repository.en_US
dc.description.abstractEpisodic increases in cerebrovascular perfusion and shear stress may have beneficial impacts on endothelial function that improve brain health. We hypothesized that water immersion to the level of the right atrium in humans would increase cerebral perfusion. We continuously measured, in 9 young (means ± SD, 24.6 ± 2.0 yr) healthy men, systemic hemodynamic variables along with blood flows in the common carotid and middle and posterior cerebral arteries during controlled filling and emptying of a water tank to the level of the right atrium. Mean arterial pressure (80 ± 9 vs. 91 ± 12 mmHg, P < 0.05), cardiac output (4.8 ± 0.7 vs. 5.1 ± 0.6 l/min, P < 0.05) and end-tidal carbon dioxide (PetCO2, 39.5 ± 2.0 vs. 44.4 ± 3.5 mmHg, P < 0.05) increased with water immersion, along with middle (59 ± 6 vs. 64 ± 6 cm/s, P < 0.05) and posterior cerebral artery blood flow velocities (41 ± 9 vs. 44 ± 10 cm/s, P < 0.05). These changes were reversed when the tank was emptied. Water immersion is associated with hemodynamic and PetCO2 changes, which increase cerebral blood velocities in humans. This study provides an evidence base for future studies to examine the potential additive effect of exercise in water on improving cerebrovascular health.en_US
dc.publisherAmerican Physiological Societyen_US
dc.relation.ispartofseriesAmerican Journal of Physiology - Regulatory, Integrative and Comparative Physiology;
dc.titleCardiovascular responses to water immersion in humans: Impact on cerebral perfusionen_US

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